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Our mission is to process and harmonize Alzheimer’s Disease genetic and genomic data to facilitate and expedite gene discovery and drug target identification.

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Whole-genome and whole-exome sequencing data are processed into CRAMs, gVCFs and then joint called into project level VCFs.

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GCAD is facilitating collaborations between cohorts and researchers studying neurodegenerative diseases from all over the world.

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    Alessandra Chesi recently joined the Department of Pathology and Laboratory Medicine in the Division of Experimental Pathology, as well as the Penn Neurodegeneration Genomics Center. Alessandra joins us from CHOP where, from 2013-2023, she was a Bioinformatic Specialist in Struan Grant’s lab and the Center for Spatial and Functional Genomics. Before joining CHOP, Alessandra worked in the laboratory […]

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    The NIA is excited to announce the release of the latest genomics data set from the Alzheimer’s Disease Sequencing Project (ADSP). The NIA Genetics of Alzheimer’s Disease Data Storage Site (NIAGADS) is a vital tool as we seek to better understand genes that increase risk for — or protection from — AD/ADRD. Researchers can now access […]

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